Protein citrullination marks myelin protein aggregation and disease progression in mouse ALS models

Increased protein citrullination (PC) and dysregulated protein arginine deiminase (PAD) activity have been observed in several neurodegenerative diseases. PC is a posttranslational modification catalyzed by the PADs. PC converts peptidyl-arginine to peptidyl-citrulline, thereby reducing the positive...

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Detalles Bibliográficos
Autores principales: Yusuf, Issa O., Qiao, Tao, Parsi, Sepideh, Tilvawala, Ronak, Thompson, Paul R., Xu, Zuoshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458309/
https://www.ncbi.nlm.nih.gov/pubmed/36076282
http://dx.doi.org/10.1186/s40478-022-01433-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458309/
https://www.ncbi.nlm.nih.gov/pubmed/36076282
http://dx.doi.org/10.1186/s40478-022-01433-5

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