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SIRT3-Mediated CypD-K166 Deacetylation Alleviates Neuropathic Pain by Improving Mitochondrial Dysfunction and Inhibiting Oxidative Stress

Numerous studies have shown that mitochondrial dysfunction manifested by increased mitochondrial permeability transition pore (mPTP) opening and reactive oxygen species (ROS) level, and decreased mitochondrial membrane potential (MMP) plays an important role in the development of neuropathic pain. S...

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Detalles Bibliográficos
Autores principales: Yan, Binbin, Liu, Qiang, Ding, Xiaobao, Lin, Yuwen, Jiao, Xiaowei, Wu, Yuqing, Miao, Huihui, Zhou, Chenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458368/
https://www.ncbi.nlm.nih.gov/pubmed/36092157
http://dx.doi.org/10.1155/2022/4722647