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Overcoming Basal Autophagy, Kangai Injection Enhances Cisplatin Cytotoxicity by Regulating FOXO3a-Dependent Autophagic Cell Death and Apoptosis in Human Lung Adenocarcinoma A549/DDP Cells

Cisplatin resistance is one of the major obstacles in the treatment of nonsmall cell lung cancer (NSCLC). Kangai injection (KAI), a Chinese herbal medicine, has been used in tumors as adjuvant treatment, but its exact antitumor mechanism is still unclear. In this study, we first demonstrated that ci...

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Detalles Bibliográficos
Autores principales: Zhou, Huan, Pan, Pengyu, Zhao, Qiuyu, Liu, Wenjun, Sun, Ye, Wang, Jianbo, Liu, Chunying, Wang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458369/
https://www.ncbi.nlm.nih.gov/pubmed/36093402
http://dx.doi.org/10.1155/2022/6022981