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Overcoming Basal Autophagy, Kangai Injection Enhances Cisplatin Cytotoxicity by Regulating FOXO3a-Dependent Autophagic Cell Death and Apoptosis in Human Lung Adenocarcinoma A549/DDP Cells
Cisplatin resistance is one of the major obstacles in the treatment of nonsmall cell lung cancer (NSCLC). Kangai injection (KAI), a Chinese herbal medicine, has been used in tumors as adjuvant treatment, but its exact antitumor mechanism is still unclear. In this study, we first demonstrated that ci...
Autores principales: | Zhou, Huan, Pan, Pengyu, Zhao, Qiuyu, Liu, Wenjun, Sun, Ye, Wang, Jianbo, Liu, Chunying, Wang, Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458369/ https://www.ncbi.nlm.nih.gov/pubmed/36093402 http://dx.doi.org/10.1155/2022/6022981 |
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