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The toxin–antitoxin RNA guards of CRISPR-Cas evolved high specificity through repeat degeneration
Recent discovery of ectopic repeats (outside CRISPR arrays) provided unprecedented insights into the nondefense roles of CRISPR-Cas. A striking example is the addiction module CreTA (CRISPR-regulated toxin–antitoxins), where one or two (in most cases) ectopic repeats produce CRISPR-resembling antito...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458426/ https://www.ncbi.nlm.nih.gov/pubmed/36018812 http://dx.doi.org/10.1093/nar/gkac712 |