Programmable RNA base editing with a single gRNA-free enzyme

Programmable RNA editing enables rewriting gene expression without changing genome sequences. Current tools for specific RNA editing dependent on the assembly of guide RNA into an RNA/protein complex, causing delivery barrier and low editing efficiency. We report a new gRNA-free system, RNA editing...

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Detalles Bibliográficos
Autores principales: Han, Wenjian, Huang, Wendi, Wei, Tong, Ye, Yanwen, Mao, Miaowei, Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458445/
https://www.ncbi.nlm.nih.gov/pubmed/36029126
http://dx.doi.org/10.1093/nar/gkac713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458445/
https://www.ncbi.nlm.nih.gov/pubmed/36029126
http://dx.doi.org/10.1093/nar/gkac713

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