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ATRX histone binding and helicase activities have distinct roles in neuronal differentiation
ATRX is a chromatin remodeler, which is mutated in ATRX syndrome, a neurodevelopmental disorder. ATRX mutations that alter histone binding or chromatin remodeling activities cluster in the PHD finger or the helicase domain respectively. Using engineered mouse embryonic stem cells that exclusively ex...
Autores principales: | Bieluszewska, Anna, Wulfridge, Phillip, Doherty, John, Ren, Wenqing, Sarma, Kavitha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458459/ https://www.ncbi.nlm.nih.gov/pubmed/35998910 http://dx.doi.org/10.1093/nar/gkac683 |
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