Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNA(Leu(UUR)) with a pathogenic A2748G mutation

Mitochondrial tRNAs are indispensable for the intra-mitochondrial translation of genes related to respiratory subunits, and mutations in mitochondrial tRNA genes have been identified in various disease patients. However, the molecular mechanism underlying pathogenesis remains unclear due to the lack...

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Detalles Bibliográficos
Autores principales: Tani, Haruna, Ishikawa, Kaori, Tamashiro, Hiroaki, Ogasawara, Emi, Yasukawa, Takehiro, Matsuda, Shigeru, Shimizu, Akinori, Kang, Dongchon, Hayashi, Jun-Ichi, Wei, Fan-Yan, Nakada, Kazuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458463/
https://www.ncbi.nlm.nih.gov/pubmed/35998911
http://dx.doi.org/10.1093/nar/gkac699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458463/
https://www.ncbi.nlm.nih.gov/pubmed/35998911
http://dx.doi.org/10.1093/nar/gkac699

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