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RUV-III-NB: normalization of single cell RNA-seq data

Normalization of single cell RNA-seq data remains a challenging task. The performance of different methods can vary greatly between datasets when unwanted factors and biology are associated. Most normalization methods also only remove the effects of unwanted variation for the cell embedding but not...

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Detalles Bibliográficos
Autores principales: Salim, Agus, Molania, Ramyar, Wang, Jianan, De Livera, Alysha, Thijssen, Rachel, Speed, Terence P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458465/
https://www.ncbi.nlm.nih.gov/pubmed/35758618
http://dx.doi.org/10.1093/nar/gkac486