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Detecting critical transition signals from single-cell transcriptomes to infer lineage-determining transcription factors

Analyzing single-cell transcriptomes promises to decipher the plasticity, heterogeneity, and rapid switches in developmental cellular state transitions. Such analyses require the identification of gene markers for semi-stable transition states. However, there are nontrivial challenges such as unexpl...

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Detalles Bibliográficos
Autores principales: Yang, Xinan H, Goldstein, Andrew, Sun, Yuxi, Wang, Zhezhen, Wei, Megan, Moskowitz, Ivan P, Cunningham, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458468/
https://www.ncbi.nlm.nih.gov/pubmed/35640613
http://dx.doi.org/10.1093/nar/gkac452