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Detecting critical transition signals from single-cell transcriptomes to infer lineage-determining transcription factors
Analyzing single-cell transcriptomes promises to decipher the plasticity, heterogeneity, and rapid switches in developmental cellular state transitions. Such analyses require the identification of gene markers for semi-stable transition states. However, there are nontrivial challenges such as unexpl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458468/ https://www.ncbi.nlm.nih.gov/pubmed/35640613 http://dx.doi.org/10.1093/nar/gkac452 |