GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection

Cellular necrosis during Mycobacterium tuberculosis (Mtb) infection promotes both immunopathology and bacterial dissemination. Glutathione peroxidase-4 (Gpx4) is an enzyme that plays a critical role in preventing iron-dependent lipid peroxidation–mediated cell death (ferroptosis), a process previous...

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Detalles Bibliográficos
Autores principales: Amaral, Eduardo P., Foreman, Taylor W., Namasivayam, Sivaranjani, Hilligan, Kerry L., Kauffman, Keith D., Barbosa Bomfim, Caio Cesar, Costa, Diego L., Barreto-Duarte, Beatriz, Gurgel-Rocha, Clarissa, Santana, Monique Freire, Cordeiro-Santos, Marcelo, Du Bruyn, Elsa, Riou, Catherine, Aberman, Kate, Wilkinson, Robert John, Barber, Daniel L., Mayer-Barber, Katrin D., Andrade, Bruno B., Sher, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458471/
https://www.ncbi.nlm.nih.gov/pubmed/36069923
http://dx.doi.org/10.1084/jem.20220504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458471/
https://www.ncbi.nlm.nih.gov/pubmed/36069923
http://dx.doi.org/10.1084/jem.20220504

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