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The effects of CD148 Q276P/R326Q polymorphisms in A431D epidermoid cancer cell proliferation and epidermal growth factor receptor signaling

BACKGROUND: CD148 is a transmembrane protein tyrosine phosphatase that is expressed in multiple cell types. Previous studies have shown that CD148 dephosphorylates growth factor receptors and their signaling molecules, including EGFR and ERK1/2, and negatively regulates cancer cell growth. Furthermo...

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Detalles Bibliográficos
Autores principales: He, Lilly, Takahashi, Keiko, Pasic, Lejla, Narui, Chikage, Ellinger, Philipp, Grundmann, Manuel, Takahashi, Takamune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458507/
https://www.ncbi.nlm.nih.gov/pubmed/34791835
http://dx.doi.org/10.1002/cnr2.1566