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L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry

There is an urgent need for development of drugs that are able to reverse the adverse effects of opioids on breathing and arterial blood-gas (ABG) chemistry while preserving opioid analgesia. The present study describes the effects of bolus injections of N-acetyl-L-cysteine (L-NAC, 500 μmol/kg, IV)...

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Detalles Bibliográficos
Autores principales: Getsy, Paulina M., Baby, Santhosh M., May, Walter J., Lewis, Tristan H.J., Bates, James N., Hsieh, Yee-Hsee, Gaston, Benjamin, Lewis, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458628/
https://www.ncbi.nlm.nih.gov/pubmed/35724513
http://dx.doi.org/10.1016/j.biopha.2022.113277