A biomarker of aging, p16, predicts peripheral neuropathy in women receiving adjuvant taxanes for breast cancer

Identifying patients at higher risk of chemotherapy-induced peripheral neuropathy (CIPN) is a major unmet need given its high incidence, persistence, and detrimental effect on quality of life. We determined if the expression of p16, a biomarker of aging and cellular senescence, predicts CIPN in a pr...

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Detalles Bibliográficos
Autores principales: Mitin, Natalia, Nyrop, Kirsten A., Strum, Susan L., Knecht, Anne, Carey, Lisa A., Reeder-Hayes, Katherine E., Claire Dees, E., Jolly, Trevor A., Kimmick, Gretchen G., Karuturi, Meghan S., Reinbolt, Raquel E., Speca, JoEllen C., O’Hare, Erin A., Muss, Hyman B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458644/
https://www.ncbi.nlm.nih.gov/pubmed/36075910
http://dx.doi.org/10.1038/s41523-022-00473-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458644/
https://www.ncbi.nlm.nih.gov/pubmed/36075910
http://dx.doi.org/10.1038/s41523-022-00473-3

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