Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods

Polygenic risk scores (PRS) have been successfully developed for the prediction of human diseases and complex traits in the past years. For drug response prediction in randomized clinical trials, a common practice is to apply PRS built from a disease genome-wide association study (GWAS) directly to...

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Detalles Bibliográficos
Autores principales: Zhai, Song, Zhang, Hong, Mehrotra, Devan V., Shen, Judong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458667/
https://www.ncbi.nlm.nih.gov/pubmed/36075892
http://dx.doi.org/10.1038/s41467-022-32407-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458667/
https://www.ncbi.nlm.nih.gov/pubmed/36075892
http://dx.doi.org/10.1038/s41467-022-32407-9

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