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Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods
Polygenic risk scores (PRS) have been successfully developed for the prediction of human diseases and complex traits in the past years. For drug response prediction in randomized clinical trials, a common practice is to apply PRS built from a disease genome-wide association study (GWAS) directly to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458667/ https://www.ncbi.nlm.nih.gov/pubmed/36075892 http://dx.doi.org/10.1038/s41467-022-32407-9 |