Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling

Multidomain proteins composed of individual domains connected by flexible linkers pose a challenge for structural studies due to their intrinsic conformational dynamics. Integrated modelling approaches provide a means to characterise protein flexibility by combining experimental measurements with mo...

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Detalles Bibliográficos
Autores principales: Kausas, Marius, Esposito, Diego, Rittinger, Katrin, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458678/
https://www.ncbi.nlm.nih.gov/pubmed/36076045
http://dx.doi.org/10.1038/s41598-022-18890-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458678/
https://www.ncbi.nlm.nih.gov/pubmed/36076045
http://dx.doi.org/10.1038/s41598-022-18890-6

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