Galectin-3 critically mediates the hepatoprotection conferred by M2-like macrophages in ACLF by inhibiting pyroptosis but not necroptosis signalling

We previously documented that M2-like macrophages exert a hepatoprotective effect in acute-on-chronic liver failure (ACLF) by inhibiting necroptosis signalling. Nevertheless, the molecular mechanism behind this hepatoprotection still needs to be further dissected. Galectin-3 (GAL3) has been reported...

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Detalles Bibliográficos
Autores principales: Bai, Li, Lu, Wang, Tang, Shan, Tang, Huixin, Xu, Manman, Liang, Chen, Zheng, Sujun, Liu, Shuang, Kong, Ming, Duan, Zhongping, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458748/
https://www.ncbi.nlm.nih.gov/pubmed/36075893
http://dx.doi.org/10.1038/s41419-022-05181-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458748/
https://www.ncbi.nlm.nih.gov/pubmed/36075893
http://dx.doi.org/10.1038/s41419-022-05181-1

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