Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma

Autologous T cells transduced to express a high affinity T-cell receptor specific to NY-ESO-1 (letetresgene autoleucel, lete-cel) show promise in the treatment of metastatic synovial sarcoma, with 50% overall response rate. The efficacy of lete-cel treatment in 45 synovial sarcoma patients (NCT01343...

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Detalles Bibliográficos
Autores principales: Gyurdieva, Alexandra, Zajic, Stefan, Chang, Ya-Fang, Houseman, E. Andres, Zhong, Shan, Kim, Jaegil, Nathenson, Michael, Faitg, Thomas, Woessner, Mary, Turner, David C., Hasan, Aisha N., Glod, John, Kaplan, Rosandra N., D’Angelo, Sandra P., Araujo, Dejka M., Chow, Warren A., Druta, Mihaela, Demetri, George D., Van Tine, Brian A., Grupp, Stephan A., Fine, Gregg D., Eleftheriadou, Ioanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458750/
https://www.ncbi.nlm.nih.gov/pubmed/36075914
http://dx.doi.org/10.1038/s41467-022-32491-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458750/
https://www.ncbi.nlm.nih.gov/pubmed/36075914
http://dx.doi.org/10.1038/s41467-022-32491-x

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