Overexpression of estrogen receptor GPER1 and G1 treatment reduces SARS-CoV-2 infection in BEAS-2B bronchial cells

Gender-bias in COVID-19 severity has been suggested by clinical data. Experimental data in cell and animal models have demonstrated the role of sex hormones, particularly estrogens, in viral infections such as in COVID-19. SARS-CoV-2 uses ACE2 as a receptor to recognize host cells, and the protease...

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Detalles Bibliográficos
Autores principales: Costa, Angelica Jardim, Lemes, Robertha Mariana Rodrigues, Bartolomeo, Cynthia Silva, Nunes, Tamires Alves, Pereira, Gabriela Cruz, Oliveira, Rafaela Brito, Gomes, Alexandre Lopes, Smaili, Soraya Soubhi, Maciel, Rui Monteiro de Barros, Newson, Louise, Ramirez, Ana Lopez, Okuda, Liria Hiromi, Prado, Carla Máximo, Stilhano, Roberta Sessa, Ureshino, Rodrigo Portes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458763/
https://www.ncbi.nlm.nih.gov/pubmed/36096380
http://dx.doi.org/10.1016/j.mce.2022.111775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458763/
https://www.ncbi.nlm.nih.gov/pubmed/36096380
http://dx.doi.org/10.1016/j.mce.2022.111775

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