Interleukin-6-derived cancer-associated fibroblasts activate STAT3 pathway contributing to gemcitabine resistance in cholangiocarcinoma

Cancer-associated fibroblasts (CAFs) are the dominant component of the tumor microenvironment (TME) that can be beneficial to the generation and progression of cancer cells leading to chemotherapeutic failure via several mechanisms. Nevertheless, the roles of CAFs on anti-cancer drug response need m...

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Detalles Bibliográficos
Autores principales: Kittirat, Yingpinyapat, Suksawat, Manida, Thongchot, Suyanee, Padthaisong, Sureerat, Phetcharaburanin, Jutarop, Wangwiwatsin, Arporn, Klanrit, Poramate, Sangkhamanon, Sakkarn, Titapun, Attapol, Loilome, Watcharin, Saya, Hideyuki, Namwat, Nisana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459012/
https://www.ncbi.nlm.nih.gov/pubmed/36091805
http://dx.doi.org/10.3389/fphar.2022.897368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459012/
https://www.ncbi.nlm.nih.gov/pubmed/36091805
http://dx.doi.org/10.3389/fphar.2022.897368

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