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Transcriptome profiles of latently- and reactivated HIV-1 infected primary CD4(+) T cells: A pooled data-analysis

The main obstacle to cure HIV-1 is the latent reservoir. Antiretroviral therapy effectively controls viral replication, however, it does not eradicate the latent reservoir. Latent CD4(+) T cells are extremely rare in HIV-1 infected patients, making primary CD4(+) T cell models of HIV-1 latency key t...

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Detalles Bibliográficos
Autores principales: Inderbitzin, Anne, Loosli, Tom, Opitz, Lennart, Rusert, Peter, Metzner, Karin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459035/
https://www.ncbi.nlm.nih.gov/pubmed/36090997
http://dx.doi.org/10.3389/fimmu.2022.915805