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A stepwise strategy integrating metabolomics and pseudotargeted spectrum–effect relationship to elucidate the potential hepatotoxic components in Polygonum multiflorum

Polygonum multiflorum (PM) Thunb., a typical Chinese herbal medicine with different therapeutic effect in raw and processed forms, has been used worldwide for thousands of years. However, hepatotoxicity caused by PM has raised considerable concern in recent decades. The exploration of toxic componen...

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Detalles Bibliográficos
Autores principales: Song, Yunfei, Yang, Jianbo, Hu, Xiaowen, Gao, Huiyu, Wang, Pengfei, Wang, Xueting, Liu, Yue, Cheng, Xianlong, Wei, Feng, Ma, Shuangcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459084/
https://www.ncbi.nlm.nih.gov/pubmed/36091795
http://dx.doi.org/10.3389/fphar.2022.935336