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In vivo imaging of tau deposition in Alzheimer’s disease using both [(18)F]-THK5317 and [(18)F]-S16: A pilot human study

OBJECTIVE: To evaluate the effectiveness of a new tracer (S)-1-(4-(6-(dimethylamino)quinoxalin-2-yl)phenoxy)-3-fluoropropan-2-ol ([(18)F]-S16), in distinguishing patients with AD from HCs. METHODS: Paired [(18)F]-S16 and [(18)F]-THK5317 scans were acquired in five patients with AD, six HCs, one subj...

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Detalles Bibliográficos
Autores principales: Fu, Liping, Zhang, Jinming, Zhou, Kaixiang, Zhang, Xiaojun, Xie, Hengge, Zhu, Mingwei, Cui, Mengchao, Wang, Ruimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459225/
https://www.ncbi.nlm.nih.gov/pubmed/36092808
http://dx.doi.org/10.3389/fnagi.2022.994750