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Precise somatic genome editing for treatment of inborn errors of immunity

Rapid advances in high throughput sequencing have substantially expedited the identification and diagnosis of inborn errors of immunity (IEI). Correction of faulty genes in the hematopoietic stem cells can potentially provide cures for the majority of these monogenic immune disorders. Given the clin...

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Detalles Bibliográficos
Autores principales: Meng, Qingzhou, Sun, Haixiang, Liu, Jianghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459235/
https://www.ncbi.nlm.nih.gov/pubmed/36091069
http://dx.doi.org/10.3389/fimmu.2022.960348