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Network Meta-analysis on Disconnected Evidence Networks When Only Aggregate Data Are Available: Modified Methods to Include Disconnected Trials and Single-Arm Studies while Minimizing Bias

BACKGROUND: Network meta-analysis (NMA) requires a connected network of randomized controlled trials (RCTs) and cannot include single-arm studies. Regulators or academics often have only aggregate data. Two aggregate data methods for analyzing disconnected networks are random effects on baseline and...

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Detalles Bibliográficos
Autores principales: Thom, Howard, Leahy, Joy, Jansen, Jeroen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459361/
https://www.ncbi.nlm.nih.gov/pubmed/35531938
http://dx.doi.org/10.1177/0272989X221097081