Olaparib, a PARP-1 inhibitor, protects retinal cells from ocular hypertension-associated oxidative damage

Glaucoma is the most common cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) and relative hypoxia in the retina stimulate the production of reactive oxygen species (ROS), which, in turn, puts the retina and optic nerve under chronic oxidative stress. Emerging evidence h...

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Detalles Bibliográficos
Autores principales: Yang, Yuting, Wu, Jihong, Lu, Wei, Dai, Yiqin, Zhang, Youjia, Sun, Xinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459396/
https://www.ncbi.nlm.nih.gov/pubmed/36092711
http://dx.doi.org/10.3389/fcell.2022.925835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459396/
https://www.ncbi.nlm.nih.gov/pubmed/36092711
http://dx.doi.org/10.3389/fcell.2022.925835

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