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Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver

Regulation of gene expression is linked to the organization of the genome. With age, chromatin alterations occur on all levels of genome organization, accompanied by changes in the gene expression profile. However, little is known about the changes in the level of transcriptional regulation. Here, w...

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Detalles Bibliográficos
Autores principales: Bozukova, Mihaela, Nikopoulou, Chrysa, Kleinenkuhnen, Niklas, Grbavac, Dora, Goetsch, Katrin, Tessarz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459415/
https://www.ncbi.nlm.nih.gov/pubmed/36082605
http://dx.doi.org/10.15252/msb.202211002