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Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver
Regulation of gene expression is linked to the organization of the genome. With age, chromatin alterations occur on all levels of genome organization, accompanied by changes in the gene expression profile. However, little is known about the changes in the level of transcriptional regulation. Here, w...
Autores principales: | Bozukova, Mihaela, Nikopoulou, Chrysa, Kleinenkuhnen, Niklas, Grbavac, Dora, Goetsch, Katrin, Tessarz, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459415/ https://www.ncbi.nlm.nih.gov/pubmed/36082605 http://dx.doi.org/10.15252/msb.202211002 |
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