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METTL3-Mediated m(6)A Modification of lncRNA MALAT1 Facilitates Prostate Cancer Growth by Activation of PI3K/AKT Signaling

Accumulating data show that N6-methyladenosine (m(6)A) methyltransferase METTL3 and long noncoding RNA MALAT1 act pivotal roles in multiple malignancies including prostate cancer (PCa). However, the role and molecular mechanism underlying METTL3-mediated m(6)A modification of MALAT1 in PCa remain un...

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Detalles Bibliográficos
Autores principales: Mao, Yuanshen, Li, Wenfeng, Weng, YiMing, Hua, Bao, Gu, Xin, Lu, Chao, Xu, Bin, Xu, Huan, Wang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459491/
https://www.ncbi.nlm.nih.gov/pubmed/36073002
http://dx.doi.org/10.1177/09636897221122997