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Hemophagocytic lymphohistiocytosis in two patients following treatment with pembrolizumab: two case reports and a literature review
BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening state of immune hyperactivation. It has the highest mortality rate among all hematological immune-related adverse events (irAEs) of immune checkpoint inhibitors (ICIs) when treating various cancers. However, the pred...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459512/ https://www.ncbi.nlm.nih.gov/pubmed/36093533 http://dx.doi.org/10.21037/tcr-22-154 |