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The clinical efficacy and limitations of dutasteride-regulated abiraterone metabolism in abiraterone-resistant patients: a prospective single-arm clinical trial in Chinese patients

BACKGROUND: The steroidal metabolism of abiraterone has been proposed to be involved in abiraterone resistance and limited approaches are available for abiraterone-resistant patients. Dutasteride regulates abiraterone metabolism in patients and might enhance the clinical efficacy of abiraterone. How...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Yang, Tao, Xu, Chengdang, Chen, Xi, Chi, Yongnan, Zhou, Weidong, Le, Wei, Bian, Cuidong, Li, Zhenfei, Huang, Shengsong, Wu, Denglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459540/
https://www.ncbi.nlm.nih.gov/pubmed/36092845
http://dx.doi.org/10.21037/tau-22-507