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CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells

BACKGROUND: Gastric cancer (GC) is one of the most common malignant tumours in China, but the efficacy of chemotherapy on GC is significantly reduced due to the occurrence of drug resistance. Some studies have shown that the expression level of CD13 is associated with tumour resistance, but whether...

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Detalles Bibliográficos
Autores principales: Xiu, Ting, Guo, Qie, Jing, Fanjing, Shi, Yunyan, Jing, Fanbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459635/
https://www.ncbi.nlm.nih.gov/pubmed/36093528
http://dx.doi.org/10.21037/tcr-22-345