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LncRNA RP11-59J16.2 aggravates apoptosis and increases tau phosphorylation by targeting MCM2 in AD

Alzheimer’s disease (AD) is a degenerative disease of central nervous system with unclear pathogenesis, accounting for 60%–70% of dementia cases. Long noncoding RNAs (LncRNAs) play an important function in the development of AD. This study aims to explore the role of differentially expressed lncRNAs...

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Detalles Bibliográficos
Autores principales: Guan, Fulin, Gao, Qichang, Dai, Xinghua, Li, Lei, Bao, Rui, Gu, Jiaao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459667/
https://www.ncbi.nlm.nih.gov/pubmed/36092938
http://dx.doi.org/10.3389/fgene.2022.824495