Cargando…

Kratom alkaloid mitragynine: Inhibition of chemotherapy-induced peripheral neuropathy in mice is dependent on sex and active adrenergic and opioid receptors

Mitragynine (MG) is an alkaloid found in Mitragyna speciosa (kratom) that is used as an herbal remedy for pain relief and opioid withdrawal. MG acts at μ-opioid and α-adrenergic receptors in vitro, but the physiological relevance of this activity in the context of neuropathic pain remains unknown. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Farkas, Daniel J., Foss, Jeffery D., Ward, Sara Jane, Rawls, Scott M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459671/ https://www.ncbi.nlm.nih.gov/pubmed/36093282 http://dx.doi.org/10.1016/j.ibneur.2022.08.007

Ejemplares similares

Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
por: Overbeek, Daniel L., et al.
Publicado: (2019)

Drug testing for mitragynine and kratom: Analytical challenges and medico‐legal considerations
por: Helander, Anders, et al.
Publicado: (2022)

Variations in mitragynine content in the naturally growing Kratom (Mitragyna speciosa) population of Thailand
por: Leksungnoen, Nisa, et al.
Publicado: (2022)

Comparative Toxicity Assessment of Kratom Decoction, Mitragynine and Speciociliatine Versus Morphine on Zebrafish (Danio rerio) Embryos
por: Damodaran, Thenmoly, et al.
Publicado: (2021)

Evaluation of the Mitragynine Content, Levels of Toxic Metals and the Presence of Microbes in Kratom Products Purchased in the Western Suburbs of Chicago
por: Prozialeck, Walter C., et al.
Publicado: (2020)

Evaluating kratom alkaloids using PHASE
por: Ellis, Christopher R., et al.
Publicado: (2020)

Editorial: The Pharmacology of Kratom and Its Alkaloids
por: Grundmann, Oliver, et al.
Publicado: (2022)

Kratom Alkaloids: Interactions With Enzymes, Receptors, and Cellular Barriers
por: Hanapi, Nur Aziah, et al.
Publicado: (2021)

Understanding the Physicochemical Properties of Mitragynine, a Principal Alkaloid of Mitragyna speciosa, for Preclinical Evaluation
por: Ramanathan, Surash, et al.
Publicado: (2015)

Mitragynine (Kratom)-Induced Cognitive Impairments in Mice Resemble Δ9-THC and Morphine Effects: Reversal by Cannabinoid CB(1) Receptor Antagonism
por: Iman, Ismail Nurul, et al.
Publicado: (2021)

Pharmacokinetics of mitragynine in man
por: Trakulsrichai, Satariya, et al.
Publicado: (2015)

The respiratory depressant effects of mitragynine are limited by its conversion to 7‐OH mitragynine
por: Hill, Rob, et al.
Publicado: (2022)

G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder
por: Gutridge, Anna M., et al.
Publicado: (2020)

Kratom: a dangerous player in the opioid crisis
por: Tayabali, Khadija, et al.
Publicado: (2018)

Directed Biosynthesis of Mitragynine Stereoisomers
por: Schotte, Carsten, et al.
Publicado: (2023)

Effects of Nutrient Fertility on Growth and Alkaloidal Content in Mitragyna speciosa (Kratom)
por: Zhang, Mengzi, et al.
Publicado: (2020)

Effects of Mitragynine and a Crude Alkaloid Extract Derived from Mitragyna speciosa Korth. on Permethrin Elimination in Rats
por: Srichana, Kachamas, et al.
Publicado: (2015)

Antinociceptive Action of Isolated Mitragynine from Mitragyna Speciosa through Activation of Opioid Receptor System
por: Shamima, Abdul Rahman, et al.
Publicado: (2012)

Kratom use disorder as a gateway to an opioid use disorder
por: Borges, A. C., et al.
Publicado: (2023)

Induction and Analysis of the Alkaloid Mitragynine Content of a Mitragyna speciosa Suspension Culture System upon Elicitation and Precursor Feeding
por: Mohamad Zuldin, Nor Nahazima, et al.
Publicado: (2013)

In silico investigation of mitragynine and 7-hydroxymitragynine metabolism
por: Limpanuparb, Taweetham, et al.
Publicado: (2019)

Recurrent seizures from chronic kratom use, an atypical herbal opioid()
por: Tatum, William O., et al.
Publicado: (2018)

Kratom-induced transaminitis with subsequent precipitated opioid withdrawal following naltrexone
por: Jensen, Aimee N., et al.
Publicado: (2021)

The Harm in Kratom
por: Drago, Joshua Z., et al.
Publicado: (2017)

Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance
por: Zhang, Mengzi, et al.
Publicado: (2022)

Seasonal and Geographic Variation in Alkaloid Content of Kratom (Mitragyna speciosa (Korth.) Havil.) from Thailand
por: Sengnon, Narumon, et al.
Publicado: (2023)

Mitragynine Attenuates Withdrawal Syndrome in Morphine-Withdrawn Zebrafish
por: Khor, Beng-Siang, et al.
Publicado: (2011)

Methadone, Buprenorphine, and Clonidine Attenuate Mitragynine Withdrawal in Rats
por: Hassan, Rahimah, et al.
Publicado: (2021)

Mitragynine inhibits hippocampus neuroplasticity and its molecular mechanism
por: Yunusa, Suleiman, et al.
Publicado: (2023)

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder
por: Gutridge, Anna M., et al.
Publicado: (2021)

Kratom ( Mitragyna speciosa ) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products
por: Manwill, Preston K., et al.
Publicado: (2022)

The Combination of Mitragynine and Morphine Prevents the Development of Morphine Tolerance in Mice
por: Fakurazi, Sharida, et al.
Publicado: (2013)

The Chemical and Pharmacological Properties of Mitragynine and Its Diastereomers: An Insight Review
por: Karunakaran, Thiruventhan, et al.
Publicado: (2022)

Respiratory effects of oral mitragynine and oxycodone in a rodent model
por: Henningfield, Jack E., et al.
Publicado: (2022)

Chemotherapy-induced peripheral neuropathy
por: Zhang, Xia, et al.
Publicado: (2017)

Kratom Use Within the Context of the Evolving Opioid Crisis and the COVID-19 Pandemic in the United States
por: Prozialeck, Walter C., et al.
Publicado: (2021)

The Potential for Kratom as an Antidepressant and Antipsychotic
por: Johnson, Lindsay E., et al.
Publicado: (2020)

Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities
por: Hanapi, N. A., et al.
Publicado: (2013)

The Antidepressant-Like and Analgesic Effects of Kratom Alkaloids are accompanied by Changes in Low Frequency Oscillations but not ΔFosB Accumulation
por: Buckhalter, Shoshana, et al.
Publicado: (2021)

Discovering dynamic plant enzyme complexes in yeast for novel alkaloid pathway identification from a medicinal plant kratom
por: Wu, Yinan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_88ml25plj21fcohdilrgsod4qe