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Global chromatin accessibility profiling analysis reveals a chronic activation state in aged muscle stem cells

Regulation of chromatin accessibility is critical for cell fate decisions. Chromatin structure responds to extrinsic environments rapidly. The traditional adult stem cell isolation approach requires tissue dissociation, which triggers stem cell activation and leads to alterations in chromatin struct...

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Detalles Bibliográficos
Autores principales: Dong, Anqi, Liu, Jing, Lin, Kangning, Zeng, Wenshu, So, Wai-Kin, Hu, Shenyuan, Cheung, Tom H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459695/
https://www.ncbi.nlm.nih.gov/pubmed/36093058
http://dx.doi.org/10.1016/j.isci.2022.104954