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Global chromatin accessibility profiling analysis reveals a chronic activation state in aged muscle stem cells
Regulation of chromatin accessibility is critical for cell fate decisions. Chromatin structure responds to extrinsic environments rapidly. The traditional adult stem cell isolation approach requires tissue dissociation, which triggers stem cell activation and leads to alterations in chromatin struct...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459695/ https://www.ncbi.nlm.nih.gov/pubmed/36093058 http://dx.doi.org/10.1016/j.isci.2022.104954 |