Coenzyme Q10 Supplementation Increases Removal of the ATXN3 Polyglutamine Repeat, Reducing Cerebellar Degeneration and Improving Motor Dysfunction in Murine Spinocerebellar Ataxia Type 3

Coenzyme Q10 (CoQ10), a well-known antioxidant, has been explored as a treatment in several neurodegenerative diseases, but its utility in spinocerebellar ataxia type 3 (SCA3) has not been explored. Herein, the protective effect of CoQ10 was examined using a transgenic mouse model of SCA3 onset. The...

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Detalles Bibliográficos
Autores principales: Wu, Yu-Ling, Chang, Jui-Chih, Sun, Hai-Lun, Cheng, Wen-Ling, Yen, Yu-Pei, Lin, Yong-Shiou, Chao, Yi-Chun, Liu, Ko-Hung, Huang, Ching-Shan, Liu, Kai-Li, Liu, Chin-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459709/
https://www.ncbi.nlm.nih.gov/pubmed/36079853
http://dx.doi.org/10.3390/nu14173593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459709/
https://www.ncbi.nlm.nih.gov/pubmed/36079853
http://dx.doi.org/10.3390/nu14173593

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