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Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives

Analogs of pyrimidine and 1,3,4-oxadiazole are two well established class of molecules proven as potent antiviral and anticancer agents in the pharmaceutical industry. We envisioned designing new molecules where these two heterocycles were conjugated with the goal of enhancing biological activity. I...

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Detalles Bibliográficos
Autores principales: El Mansouri, Az-eddine, Lachhab, Saida, Oubella, Ali, Ahmad, Mehdi, Neyts, Johan, Jochmans, Dirk, Chiu, Winston, Vangeel, Laura, De Jonghe, Steven, Morjani, Hamid, Ali, Mustapha Ait, Zahouily, Mohamed, Sanghvi, Yogesh S., Lazrek, Hassan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459830/
https://www.ncbi.nlm.nih.gov/pubmed/36101881
http://dx.doi.org/10.1016/j.molstruc.2022.134135