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PRG-1 prevents neonatal stimuli-induced persistent hyperalgesia and memory dysfunction via NSF/Glu/GluR2 signaling

Neonatal repetitive noxious stimuli (RNS) has been shown to cause long-term harmful effects on nociceptive processing, learning, and memory which persist until adulthood. Plasticity-related gene 1 (PRG-1) regulates synaptic plasticity and functional reorganization in the brain during neuronal develo...

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Detalles Bibliográficos
Autores principales: Liu, Xingfeng, Li, Site, Zhang, Wenyu, Xie, Zhuo, He, Jingxin, Zhang, Xuanwei, Yu, Shouyang, Cao, Song, Yu, Tian, Xiao, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460187/
https://www.ncbi.nlm.nih.gov/pubmed/36093041
http://dx.doi.org/10.1016/j.isci.2022.104989