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PRG-1 prevents neonatal stimuli-induced persistent hyperalgesia and memory dysfunction via NSF/Glu/GluR2 signaling
Neonatal repetitive noxious stimuli (RNS) has been shown to cause long-term harmful effects on nociceptive processing, learning, and memory which persist until adulthood. Plasticity-related gene 1 (PRG-1) regulates synaptic plasticity and functional reorganization in the brain during neuronal develo...
Autores principales: | Liu, Xingfeng, Li, Site, Zhang, Wenyu, Xie, Zhuo, He, Jingxin, Zhang, Xuanwei, Yu, Shouyang, Cao, Song, Yu, Tian, Xiao, Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460187/ https://www.ncbi.nlm.nih.gov/pubmed/36093041 http://dx.doi.org/10.1016/j.isci.2022.104989 |
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