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Reduction in Insulin Mediated ERK Phosphorylation by Palmitate in Liver Cells Is Independent of Fatty Acid Induced ER Stress

Saturated free fatty acids (FFAs) such as palmitate in the circulation are known to cause endoplasmic reticulum (ER) stress and insulin resistance in peripheral tissues. In addition to protein kinase B (AKT) signaling, extracellular signal-regulated kinase (ERK) has been implicated in the developmen...

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Detalles Bibliográficos
Autores principales: Mubarak, Sindiyan Alshaikh, Otaibi, Abeer Al, Qarni, Ali Al, Bakillah, Ahmed, Iqbal, Jahangir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460427/
https://www.ncbi.nlm.nih.gov/pubmed/36079898
http://dx.doi.org/10.3390/nu14173641