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Contribution of the co-chaperone FKBP51 in the ventromedial hypothalamus to metabolic homeostasis in male and female mice

OBJECTIVE: Steroidogenic factor 1 (SF1) expressing neurons in the ventromedial hypothalamus (VMH) have been directly implicated in whole-body metabolism and in the onset of obesity. The co-chaperone FKBP51 is abundantly expressed in the VMH and was recently linked to type 2 diabetes, insulin resista...

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Detalles Bibliográficos
Autores principales: Brix, Lea M., Toksöz, Irmak, Aman, London, Kovarova, Veronika, Springer, Margherita, Bordes, Joeri, van Doeselaar, Lotte, Engelhardt, Clara, Häusl, Alexander S., Narayan, Sowmya, Sterlemann, Vera, Yang, Huanqing, Deussing, Jan M., Schmidt, Mathias V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460553/
https://www.ncbi.nlm.nih.gov/pubmed/36007872
http://dx.doi.org/10.1016/j.molmet.2022.101579