Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms

We carried out a genome-wide association analysis including 51,194 cases of hypothyroidism and 443,383 controls. In total, 139 risk loci were associated to hypothyroidism with genes involved in lymphocyte function. Candidate genes associated with hypothyroidism were identified by using molecular qua...

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Detalles Bibliográficos
Autores principales: Mathieu, Samuel, Briend, Mewen, Abner, Erik, Couture, Christian, Li, Zhonglin, Bossé, Yohan, Thériault, Sébastien, Esko, Tõnu, Arsenault, Benoit J., Mathieu, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460554/
https://www.ncbi.nlm.nih.gov/pubmed/36093044
http://dx.doi.org/10.1016/j.isci.2022.104992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460554/
https://www.ncbi.nlm.nih.gov/pubmed/36093044
http://dx.doi.org/10.1016/j.isci.2022.104992

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