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Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms
We carried out a genome-wide association analysis including 51,194 cases of hypothyroidism and 443,383 controls. In total, 139 risk loci were associated to hypothyroidism with genes involved in lymphocyte function. Candidate genes associated with hypothyroidism were identified by using molecular qua...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460554/ https://www.ncbi.nlm.nih.gov/pubmed/36093044 http://dx.doi.org/10.1016/j.isci.2022.104992 |