Multiplexed protein profiling reveals spatial subcellular signaling networks

Protein-protein interaction networks are altered in multi-gene dysregulations in many disorders. Image-based protein multiplexing sheds light on signaling pathways to dissect cell-to-cell heterogeneity, previously masked by the bulk assays. Herein, we present a rapid multiplexed immunofluorescence (...

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Detalles Bibliográficos
Autores principales: Cai, Shuangyi, Hu, Thomas, Venkatesan, Mythreye, Allam, Mayar, Schneider, Frank, Ramalingam, Suresh S., Sun, Shi-Yong, Coskun, Ahmet F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460555/
https://www.ncbi.nlm.nih.gov/pubmed/36093051
http://dx.doi.org/10.1016/j.isci.2022.104980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460555/
https://www.ncbi.nlm.nih.gov/pubmed/36093051
http://dx.doi.org/10.1016/j.isci.2022.104980

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