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Quantitative Structure–Activity Relationship Analysis of Isosteviol-Related Compounds as Activated Coagulation Factor X (FXa) Inhibitors

Stevioside, one of the natural sweeteners extracted from stevia leaves, and its derivatives are considered to have numerous beneficial pharmacological properties, including the inhibition of activated coagulation factor X (FXa). FXa-PAR signaling is a possible therapeutic target to enhance impaired...

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Detalles Bibliográficos
Autores principales: Gackowski, Marcin, Szewczyk-Golec, Karolina, Mądra-Gackowska, Katarzyna, Pluskota, Robert, Koba, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460690/
https://www.ncbi.nlm.nih.gov/pubmed/36079779
http://dx.doi.org/10.3390/nu14173521