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Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth

Background: Despite decades of research, the pathogenesis of spontaneous preterm birth (PTB) remains largely unknown. Limited currently available data on PTB pathogenesis are based on rodent models, which do not accurately reflect the complexity of the human placenta across gestation. While much stu...

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Detalles Bibliográficos
Autores principales: Akram, Khondoker M., Frost, Lucy I., Anumba, Dilly OC.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460763/
https://www.ncbi.nlm.nih.gov/pubmed/36090032
http://dx.doi.org/10.3389/fmolb.2022.897228