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Peptidyl Prolyl Isomerase A Modulates the Liquid–Liquid Phase Separation of Proline-Rich IDPs

[Image: see text] Liquid–liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) and the action of molecular chaperones are tightly connected. An important class of molecular chaperones are peptidyl prolyl isomerases, which enhance the cis/trans-isomerization of proline. However,...

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Detalles Bibliográficos
Autores principales: Babu, Maria, Favretto, Filippo, Rankovic, Marija, Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460772/
https://www.ncbi.nlm.nih.gov/pubmed/36018855
http://dx.doi.org/10.1021/jacs.2c07149