Enzymatic Control over Reactive Intermediates Enables Direct Oxidation of Alkenes to Carbonyls by a P450 Iron-Oxo Species

[Image: see text] The aerobic oxidation of alkenes to carbonyls is an important and challenging transformation in synthesis. Recently, a new P450-based enzyme (aMOx) has been evolved in the laboratory to directly oxidize styrenes to their corresponding aldehydes with high activity and selectivity. T...

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Detalles Bibliográficos
Autores principales: Soler, Jordi, Gergel, Sebastian, Klaus, Cindy, Hammer, Stephan C., Garcia-Borràs, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460782/
https://www.ncbi.nlm.nih.gov/pubmed/35998887
http://dx.doi.org/10.1021/jacs.2c02567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460782/
https://www.ncbi.nlm.nih.gov/pubmed/35998887
http://dx.doi.org/10.1021/jacs.2c02567

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